Alaunos Therapeutics has decided to terminate its licensing agreement with Precigen, Inc. The agreement, which has been in place since 2018, was for the development of neoantigen T-cell receptors to treat solid tumor cancers. The decision is a result of Alaunos reassessing its business goals and the upcoming patent expiration of the Sleeping Beauty gene transfer platform in 2026. Despite this, Alaunos is actively pursuing its intellectual property rights for certain T-cell receptors and exploring strategic options, including mergers and partnerships, to advance its business.

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This news brief from Morningstar informs that stock futures point to further losses as investors continue to monitor the impact of President Trump's tariff day. Investors have increased predictions for significant rate cuts this year, expecting the Federal Reserve to take action to support the U.S. economy. Benchmark Treasury yields have fallen below 4% for the first time since October due to recession fears, leading investors to seek safety in government bonds. The upcoming jobs data may be overshadowed by the tariff fallout, according to CMC Markets. Among stocks to watch, Apple's shares have fallen by 0.8%.

The financial markets are reacting to various factors. Tesla's shares have declined by 1% after a 5.5% decrease on Thursday due to its heavy dependence on Chinese manufacturing. Nvidia, on the other hand, increased by 0.3% following a 7.8% fall. Chip makers Advanced Micro Devices, Qualcomm, and Broadcom are maintaining a flat to lower rate. Dell Technologies declined 0.3% after a 19% fall on Thursday. Intel's shares rose by 0.8% following a report about a preliminary agreement to form a joint venture with Taiwan Semiconductor Manufacturing. Gamestop saw a 4% increase after CEO Ryan Cohen increased his stake in the company. However, Affirm and PayPal saw a decline following steep falls on Thursday. The market is also keeping an eye on the employment report for March and Canada Labour Force Survey for March.

Shares of Dermata Therapeutics, Inc. (NASDAQ: DRMA) surged by over 57% in pre-market trading following the company's announcement of a new patent issuance in Japan for its DMT410 program, aimed at treating hyperhidrosis. Other stocks also seeing movement in pre-market trading include Ainos, Inc. (NASDAQ: AIMD), which gained 142.6% to $4.20 after dropping more than 12% on Thursday, and Safe and Green Development Corporation (NASDAQ: SGD), which saw shares rise 34.5% to $1.83.

The pre-market trading saw an increase in shares for several companies. Pinstripes Holdings Inc. (NYSE: PNST) shares rose by 17.4% to $6.18 after a dip of over 35% the previous day. Fusion Pharmaceuticals Inc. (NASDAQ: FUSN) shares climbed 12.6% to $9.50 after the company announced its alignment with the FDA on a protocol and development plan for FPI-2265. Shares of Inhibikase Therapeutics, Inc. (NASDAQ: IKT) and Intelligent Bio Solutions Inc. (NASDAQ: INBS) also experienced an increase, gaining 10.5% to $1.48 and rising respectively.

The company experienced two reverse stock splits in 2024, one in January (1-for-15) and the other in July (1-for-10). The company is currently focused on developing an oral obesity drug, which is expected to have a unique profile compared to existing and developing oral and injectable products. Previously, the company was a clinical-stage oncology-focused cell therapy company working on TCR-T cell therapy for multiple solid tumor types. However, in August 2023, the company announced a strategic shift in its focus and the winding down of its TCR-T Library Phase 1/2 Trial.

The company has been actively working to reduce costs through workforce downsizing in the third and fourth quarters of 2023. They are exploring various strategic alternatives to improve their financial situation, including mergers, acquisitions, asset sales, strategic partnerships, and capital raises. For this, they have engaged Cantor Fitzgerald Co. as a strategic advisor. However, the company has not generated any product revenue and has recorded significant net losses each year since its inception. Their net loss for the year ending December 31, 2024, was $4.6 million, and their accumulated deficit since inception in 2003 is approximately $920.4 million. It is expected that the company will continue to incur significant operating expenditures and net losses for the foreseeable future.

1) Brief Summary: The company has been showing robust growth in sales with a year-over-year increase of 80.00% and a quarterly increase of 300.00%. The short float is relatively low at 3.75%, suggesting limited bearish sentiment. However, the company has significantly negative returns on equity and investment, indicating potential financial instability. Average trading volume is high, contributing to the high relative volume of 13.87, which shows investor interest. The RSI of 92.69 is significantly high, indicating potential overbought conditions. Overall, the company's performance has been strong recently, but there are signs of potential overvaluation. 2) MARKET_SCORE: 55

: Despite the impressive sales growth and high investor interest, the negative financial ratios and potential overvaluation reflected by the high RSI could limit the upside potential in the near term. 3) PRICE_TARGET: 5.5

: Considering the current price of 4.9133 and the company's strong performance, a reasonable price target could be a 12% increase, placing it at 5.5, factoring in potential overvaluation. 4) AI_RPT_HEADLINE: Strong Sales Growth and Investor Interest contrasted by Negative Financial Ratios

-> X2 <- More SEC filing extractions (10-K, 10-Q, 8-K) Financials, risk disclosures, and business changes

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