Aptevo Therapeutics announced that two additional patients with Acute Myeloid Leukemia (AML) achieved remission within 30 days of treatment in the RAINIER dose optimization trial. The treatment involved a combination of mipletamig with standard care for patients unfit for intensive chemotherapy. Overall, 9 out of 10 patients across two trials achieved remission when receiving a combination of mipletamig, venetoclax, and azacitidine. No cytokine release syndrome (CRS) has been reported in the RAINIER trial to date.

The after-market session on Wednesday saw significant movement in the healthcare sector. Protagenic Therapeutics' stock surged by 151.6% to $0.57, bringing the market value of their outstanding shares to $4.1 million. This comes in the wake of their Q4 earnings release two days prior. Aptevo Therapeutics also saw a rise in their stock by 32.6% to $1.83, with their market cap now at $2.6 million. Genprex shares went up by 32.16% to $0.39, resulting in a market cap of $3.3 million. Klotho Neurosciences' stock grew by 12.66% to $0.23, and their market cap stands at $6.1 million.

Bloom Energy shares have seen a 12.1% increase in their trading value. This jump occurred after the company announced a strategic partnership with CoreWeave. This partnership aims to deploy Bloom Energy's fuel cells for on-site power generation at a data center. The market also noted significant pre-market movements in several other stocks.

1) Brief Summary: The data exhibits a concerning financial situation for the company. Its performance over the past month, quarter, and year has been significantly negative, with a drop of 53.22%, 71.13%, and 84.17% respectively. The company also has a high beta of 6.00, indicating a high level of volatility and risk. The negative ROI and ROE further suggest that the company has been ineffective at generating a positive return. Insider trading activity is minimal, not suggesting any strong confidence from the company's executives. 2) MARKET_SCORE: 20

: Given the company's poor performance and high volatility, there is only a 20% likelihood of an upward move. 3) PRICE_TARGET: $1.60

: Considering the current market conditions and the company's performance, a modest increase of around 16% might be expected, setting the price target at 1.60 USD. 4) AI_RPT_HEADLINE: "Company's Financial Struggles Highlighted by Poor Performance and High Volatility"

-> X2 <- More SEC filings (10-K, 10-Q, 8-K) Financials, risk disclosures, and business changes

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